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3 Skin scrapings and nail clippings may be requiredto exclude tinea. The keywords used were psoriasis, plaque psoriasis, differential diagnosis, diagnosis, and papulosquamous lesion s. Reviews and original articles published up to 1 September 2020, including case reports, assessing the description of the clinical presentations and differential diagnosis for psoriasis, were included. Psoriasis is a skin disease that causes itchy or sore patches of thick, red skin with silvery scales. Summary. The blood tests are aimed at determining the non-specific signs of inflammation (leukocytosis, an increase of erythrocyte sedimentation rate, rheumatoid factor). There is a strong association between recent infection (usually streptococcal pharyngitis) and guttate psoriasis. The diagnosis of psoriasis can be made by clinical observation without laboratory tests in most cases. The disease manifests following exposure to various triggers (e.g., infection, medication). Plaque psoriasis may be confused with: Discoid dermatitis (more itch, vesicles, dry rather than plate-scale) You usually get the patches on your elbows, knees, scalp, back, face, palms and feet, but they can show up on other parts of your body. Differential diagnosis. Skin biopsy is more informative. The rash comes on very quickly and may follow a streptococcal infection of the throat. Psoriasis is a chronic inflammatory disease that affects primarily the skin and joints. It is calculated as follows: Differential diagnosis. Nail psoriasis. The differential diagnoses of guttate psoriasis include tinea corporis, secondary syphilis, nummular eczema, and pityriasis rosea. Differential diagnosis of psoriasis including plaque psoriasis, guttate psoriasis, palmoplantar psoriasis and flexural psoriasis. Background: Psoriasis is an inflammatory skin disease presenting with erythematous and desquamative plaques with sharply demarcated margins, usually localized on extensor surface areas. 54 The PASI score is the ‘Psoriasis Area and Severity Index’, and is mainly used for evaluating the effect of interventions in clinical trials. It accounts for 2% of the total cases of psoriasis (1). Guttate psoriasis may be confused with: Discoid dermatitis (more itch, vesicles, dry rather than plate-scale) Tinea corporis (elevated border, slowly extending edge, positive mycology) Pityriasis rosea (herald patch, fir-tree distribution of oval plaques, trailing scale) Erythrodermic psoriasis may be confused with: The differential diagnosis for guttate psoriasis includes lymphomatoid papulosis, pityriasis rosea, pityriasis lichenoides chronica, tinea versicolor, and secondary syphilis, although these conditions often have distinctive presentations . The differential diagnosis includes pityriasis rosacea, tinea corporis, secondary syphilis, pityriasis lichenoides chronica, nummular dermatitis, and drug eruptions. Guttate psoriasis is a skin condition in which small, droplet-shaped, red patches appear on the arms, legs, scalp, and trunk. Guttate psoriasis Microscopic (histologic) description Parakeratosis without hyperkeratosis, acanthosis with downward elongation of rete ridges (resembles a comb), thin / no granular cell layer, suprapapillary thinning (attenuated layer of epidermal cells above tips of dermal papillae), Munro microabscesses (neutrophils in parakeratotic scale) Clinical differentiation between pityriasis lichenoides chronica (PLC) and guttate psoriasis (GP) may sometimes be a difficult task, which often requires histological analysis to reach a definitive diagnosis. Guttate psoriasis is a form of psoriasis that often appears in the wake of strep throat and other similar infections. 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