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The 357 is the more versatile, and with 38 spl. For instance, when deploying the 357 Magnum, we tested a number of fast-opening JHP loads. For a 260 grain Colt to go so fast, it would have to be loaded pretty hot, while a 158 grain 357 would be about average. .357 180 grain jhp over 2400 gives between 600-950 fps (handgun min/max) and same load fires 1143-1500 fps (min/max) from rifle. If you take a low energy HP or JHP then the .45 acp is going to do more damage to soft tissue. Both are fine calibers, and able to take deer out to 100 yards or so. What is the difference between .357 Magnum and .45 Colt? The .44 Magnum can stretch that a bit more, with the ideal range being 50 to 100 yards—only a marginal increase over .357 and .45 Colt. After the second fight, I went back to the 357 mag. SAAMI Standard MAP (Operating pressures) 45 Colt operates circa 14,000 psi piezo. The modern sport of cowboy action shooting has resulted in .45 Colt carbines being offered for the first time. the 45 colt has the edge in power however it also had the edge in cost to shoot unless you hand load. The .45 acp practice round hps & jphs are typically 230 gn moving at around 700 fps with about 400 ft lbs of energy. A 158 Grain 357 load leaves an 18 inch barrel at about 1830 FPS. the easiest to find ammo and components for. (C45S are more efficient at burning powder than 45 Colt) Brass is reloaded many times and if cared for will last nearly forever at cowboy loads pressure. The 45 Colt has slightly more potential, _if_ you handload for it,but in factory loads the difference is negligible. With gravity acting the same on both, at 200 yards they could be about the same as far as drop. A 260 Grain 45 Colt load leaves an 18 inch barrel at about 1850 FPS. .357 Magnum operates at 35,000 psi piezo. The .357 and .45 Colt are best at bowhunting distances inside 50 yards. Well if you include the premium 45 LC loads from Buffalo Bore then the 357 is completely out classed by the 45 colt as it will be approching and even exceeding the 44 magnum in power. The .45 ACP cannot be relied on to bring down medium sized game animals like deer where as the .357 Magnum (with the right bullets and load) is … Muzzle energy of handgun between 143 and 360 foot pounds. If you took a round nose FMJ for both the .357 is going to out perform a .45 acp. Standard Projectile weights are significantly different . For sure use more powder - maybe 25% more. Yes, I know you can get 180 grain 45 Colt bullets but I feel most would use a larger, more period correct lead cast bullet in the 45. I obviously won both, but the 357 magnum was far more efficient, and would have done better in the second than the 45acp. Historically, it was never chambered in rifles. Low energy as in practice rounds for both. 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